O-DSMT Powder

Buy O-DSMT Powder | High-Purity O-Desmethyltramadol Research Chemical

Our O-DSMT Powder contains O-Desmethyltramadol, the main active metabolite of tramadol, known for its potent opioid analgesic properties. Synthesized via an eco-friendly, industrially scalable process, this compound is highly pure (>99%) and widely used in advanced scientific research focusing on opioid receptor pharmacology and pain management.

Key Features

• Chemical Name: O-Desmethyltramadol (Desmetramadol)

• Purity: >99% (HPLC verified)

• Molecular Formula: C16H25NO2

• Form: Fine white powder

• Potency: More potent μ-opioid receptor agonist than tramadol itself

• Synthesis: Produced via demethylation of tramadol using potassium hydroxide in alcoholic solvents, yielding high purity and high yield (88-95%)

Research Applications

O-DSMT is extensively studied for its enhanced analgesic efficacy compared to tramadol, acting as a high-affinity ligand for μ- and δ-opioid receptors. It is valuable in research on pain modulation, opioid pharmacodynamics, and potential therapeutic applications, especially in subjects with CYP2D6 enzyme variability affecting tramadol metabolism.

Safety and Handling

• Strictly for research use only; not approved for human consumption

• Handle with appropriate personal protective equipment (PPE) in well-ventilated labs

• Avoid skin and eye contact; rinse immediately if exposure occurs

• Store in a cool, dry place away from heat and direct sunlight

Packaging and Shipping

• Securely packaged to maintain compound integrity

• Discreet and reliable shipping available within Canada

• Compliance with all applicable laws and regulations is the buyer’s responsibility